Atenolol Granules

(Product under development)
Atenolol GranulesAtenolol is a selective β1 receptor antagonist, a drug belonging to the group of beta blockers (sometimes written β-blockers), a class of drugs used primarily in cardiovascular diseases.

Introduced in 1976, atenolol was developed as a replacement for propranolol in the treatment of hypertension. The chemical works by slowing down the heart and reducing its workload.

Unlike propranolol, atenolol does not pass through the blood-brain barrier thus avoiding various central nervous system side effects.

Atenolol is one of the most widely used β-blockers in the United Kingdom and was once the first-line treatment for hypertension.

The role for β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line, as they perform less appropriately or effectively than newer drugs, particularly in the elderly.

Some evidence suggests that even in normal doses the most frequently used β-blockers carry an unacceptable risk of provoking type 2 diabetes.

Available Form:
Atenolol Granules
Atenolol Pellets

Umang Pharmatech equipments used for production of Atenolol Granules:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.


Atenolol Granules
Systematic (IUPAC) Name
Atenolol Granules
Identifiers
Atenolol Granules
Chemical data
(RS)-2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide
CAS number : 29122-68-7
ATC code : C07AB03
PubChem : CID 2249
IUPHAR ligand : 548
DrugBank : APRD00172
ChemSpider : 2162
UNII : 50VV3VW0TI
KEGG : D00235
ChEMBL : CHEMBL24
Formula : C14H22N2O3
Mol. mass : 266.336 g/mol


* All transactions are carried out in conformity with patent laws applicable in the user country. Active pharmaceutical ingredients or formulations thereof will not be supplied in countries where the same is under patent protection except as and if permitted under law of the country for research and development purposes only.
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