Diltiazem Granules

Diltiazem GranulesDiltiazem is a non-dihydropyridine (non-DHP) member of the class of drugs known as calcium channel blockers, used in the treatment of hypertension, angina pectoris, and some types of arrhythmia.

It is also an effective preventive medication for migraine. It is a class 3 anti-anginal drug, and a class IV antiarrhythmic.

It is a common adulterant of cocaine seized in the UK, and has been found to reduce cocaine cravings in rats, indicating that it may prolong the "high" (see below). It incites very minimal reflex sympathetic changes. It is based upon a 1,4-thiazepine ring.

Diltiazem is metabolized by and acts as an inhibitor of the CYP3A4 enzyme.

Dose:
Diltiazem 120 mg

Available Forms:
Diltiazem Hcl SR Granules
Diltiazem Pellets

Umang Pharmatech equipments used for production of Diltiazem Granules:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Diltiazem Granules
Systematic (IUPAC) Name
Diltiazem Granules
Identifiers
Diltiazem Granules
Chemical data
cis-(+)-[2-(2-dimethylaminoethyl)-5-(4-methoxyphenyl)-3-oxo-6-thia-2-azabicyclo[5.4.0]undeca-7,9,11-trien-4-yl]ethanoate
CAS number : 42399-41-7
ATC code : C08DB01
PubChem : CID 39186
DrugBank : APRD00473
ChemSpider : 35850
UNII : EE92BBP03H
KEGG : D07845
ChEMBL : CHEMBL23
Formula : C22H26N2O4S
Mol. mass : 414.519 gmol


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