Methotrexate Granules

(Product under development)
Methotrexate GranulesMethotrexate (rINN), abbreviated MTX and formerly known asamethopterin, is an antimetabolite and antifolate drug.

It is used in treatment of cancer,autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions.

It acts by inhibiting the metabolism of folic acid. Methotrexate began to replace the more toxic antifolate aminopterin starting in the 1950s. The drug was developed by Yellapragada Subbarao.

Available Form:
Methotrexate Granules
Methotrexate Pellets

Umang Pharmatech equipments used for production of Methotrexate Granules:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Methotrexate Granules
Systematic (IUPAC) Name
Methotrexate Granules
Identifiers
Methotrexate Granules
Chemical data
(2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}
benzoyl)amino]pentanedioic acid
CAS number : 59-05-2
ATC code : L01BA01 L04AX03
PubChem : CID 126941
DrugBank : APRD00353
ChemSpider : 112728
UNII : YL5FZ2Y5U1
KEGG : D00142
ChEMBL : CHEMBL34259
Formula : C20H22N8O5>
Mol. mass : 454.44 g/mol


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