Valsartan Granules

(Product under development)
Valsartan GranulesValsartan (Angiotan) is an angiotensin II receptor antagonist (more commonly called an "ARB", or angiotensin receptor blocker), with particularly high affinity for the type I (AT1) angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure.

In the U.S., valsartan is indicated for treatment of high blood pressure, congestive heart failure (CHF), or post-myocardial infarction (MI). In 2005, Angiotan was prescribed more than 12 million times in the United States and global sales were approximately $6.1 billion in 2010.

A study released by the Journal of Clinical Investigation in 2007 found some efficacy in the use of valsartan in the treatment and prevention of Alzheimer's disease (in a mouse model) although such use is considered to be highly experimental.

Available Form:
Valsartan Granules
Valsartan Pellets

Umang Pharmatech equipments used for production of Valsartan Granules:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.


Valsartan Granules
Systematic (IUPAC) Name
Valsartan Granules
Identifiers
Valsartan Granules
Chemical data
(S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)
pentanamido]butanoic acid
CAS number : 137862-53-4
ATC code : C09CA03
PubChem : CID 60846
DrugBank : APRD00133
ChemSpider : 54833
UNII : 80M03YXJ7I
KEGG : D00400
ChEBI : CHEBI:9927
ChEMBL : CHEMBL1069
Formula : C24H29N5O3
Mol. mass : 435.519 g/mol


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