Abacavir Pellets

(Product under development)
Abacavir PelletsAbacavir (ABC) is a nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. It is available under the trade name Ziagen (ViiV Healthcare) and in the combination formulations Trizivir (abacavir, zidovudine and lamivudine) and Kivexa/Epzicom(abacavir and lamivudine).

It has been well tolerated: the main side effect is hypersensitivity, which can be severe, and in rare cases, fatal.

Genetic testing can indicate whether an individual will be hypersensitive; over 90% of patients can safely take abacavir. However, in a separate study, the risk of heart attack increased by nearly 90%.

Viral strains that are resistant to zidovudine (AZT) or lamivudine (3TC) are generally sensitive to abacavir, whereas some strains that are resistant to AZT and 3TC are not as sensitive to abacavir.

Available Form:
Abacavir Pellets
Abacavir Granules

Umang Pharmatech equipments used for production of Abacavir Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Abacavir Pellets
Systematic (IUPAC) Name
Abacavir Pellets
Identifiers
Abacavir Pellets
Chemical data
{(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
CAS number : 136470-78-5
ATC code : J05AF06
PubChem : CID 441300
DrugBank : APRD00216
ChemSpider : 390063
UNII : WR2TIP26VS
KEGG : D07057
ChEMBL : CHEMBL1380
Formula : C14H18N6O
Mol. mass : 286.332 g/mol


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