Diphenhydramine Pellets

(Product under development)
Diphenhydramine PelletsDiphenhydramine hydrochloride is a first-generation antihistamine mainly used to treat allergies. Like most other first-generation antihistamines, the drug also has a powerful hypnotic effect, and for this reason is often used as a nonprescription sleep aid and a mild anxiolytic. The drug also acts as anantiemetic.

It is produced and marketed under the trade name Benadryl by McNeil-PPC in the U.S., Canada and South Africa (other trade names in other countries: Dimedrol, Daedalon). It is also found in the name-brand products Nytol, Unisom,Tylenol PM, Midol PM and Advil PM, though some Unisom products contain doxylamineinstead.

It is available as an over-the-counter (OTC) or prescribed HCl injectable. It may also be used for the treatment of extrapyramidal side-effects of many antipsychotics, such as the tremors that haloperidol can cause.

In addition, injectable diphenhydramine can be used for life-threatening reactions (anaphylaxis) to allergens such as bee stings, peanuts, or latex, rather than risking the side-effects of epinephrine. It is a member of the ethanolamine class ofantihistaminergic agents. An alternative IUPAC name is [2-(diphenylmethoxy)ethyl]dimethylamine.

Diphenhydramine was one of the first known antihistamines, invented in 1943 by Dr. George Rieveschl, a former professor at the University of Cincinnati. In 1946, it became the first prescription antihistamine approved by the U.S. Food and Drug Administration (FDA).

Available Forms:
Diphenhydramine Pellets
Diphenhydramine Granulers

Umang Pharmatech equipments used for production of Diphenhydramine Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Diphenhydramine Pellets
Systematic (IUPAC) Name
Diphenhydramine Pellets
Identifiers
Diphenhydramine Pellets
Chemical data
2-(diphenylmethoxy-N,N-dimethyletha-namine
CAS number : 58-73-1
ATC code : D04AA32 D04AA33,R06AA02
PubChem : CID 3100
DrugBank : APRD00587
ChemSpider : APRD00587
UNII : 8GTS82S83M 
KEGG : D00669
ChEMBL : CHEMBL1620
Formula : C17H21NO
Mol. mass : 255.355 g/mol


* All transactions are carried out in conformity with patent laws applicable in the user country. Active pharmaceutical ingredients or formulations thereof will not be supplied in countries where the same is under patent protection except as and if permitted under law of the country for research and development purposes only.
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