Doxazosin Pellets

(Product under development)
Doxazosin PelletsDoxazosin mesylate, a quinazoline compound sold under the brand names Cardura and Carduran, is an alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia (BPH).

On February 22, 2005, the US FDA approved a sustained release form of doxazosin.

It is an alpha-1 adrenergic receptor blocker that inhibits the binding of norepinephrine (released from sympathetic nerve terminals) to the alpha-1 receptors on the membrane of vascular smooth muscle cells.

The primary effect of this inhibition is relaxed vascular smooth muscle tone (vasodilation), which decreases peripheral vascular resistance, leading to decreased blood pressure.

Available Forms:
Doxazosin Pellets
Doxazosin Granulers

Umang Pharmatech equipments used for production of Doxazosin Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Doxazosin Pellets
Systematic (IUPAC) name
Doxazosin Pellets
Identifiers
Doxazosin Pellets
Chemical data
(RS)-2-{4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine
CAS number : 74191-85-8
ATC code : C02CA04
PubChem : CID 3157
DrugBank : APRD00474
ChemSpider : 3045
UNII : NW1291F1W8
KEGG : D07874
ChEBI : CHEBI:4708
ChEMBL : CHEMBL707
Formula : C23H25N5O5
Mol. mass : 451.475 g/mol


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