Lamivudine Pellets

(Product under development)
Lamivudine PelletsLamivudine (2',3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).

It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV.

Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver.

Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.

Availble Form:
Lamivudine Pellets
Lamivudine Granules

Umang Pharmatech equipments used for production of Lamivudine Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.


Lamivudine Pellets
Systematic (IUPAC) Name
Lamivudine Pellets
Identifiers
Lamivudine Pellets
Chemical data
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
CAS number : 134678-17-4
ATC code : J05AF05
PubChem : CID 73339
DrugBank : APRD00681
ChemSpider : 66068
UNII : 2T8Q726O95
KEGG : D00353
ChEMBL : CHEMBL141
Synonyms : L-2',3'-dideoxy-3'-thiacytidine
Formula : C8H11N3O3S
Mol. mass : 229.26 g/mol


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