Lamotrigine Pellets

(Product under development)
Lamotrigine PelletsILamotrigine, marketed in the US as Lamictal by GlaxoSmithKline, is ananticonvulsant drug used in the treatment of epilepsy and bipolar disorder.

It is also used as an adjunct in treating depression, though this is considered off-label usage. For epilepsy, it is used to treat partial seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome.

Like many other anticonvulsant medications, Lamotrigine also seems to act as an effective mood stabilizer, and in fact has been the only U.S.

Food and Drug Administration (FDA)-approved drug for this purpose since lithium, a drug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type I.

Chemically unrelated to other anticonvulsants (due to lamotrigine's being a phenyltriazine), lamotrigine has relatively few side-effects and does not require blood monitoring in monotherapy.

Lamotrigine is generally accepted to be a member of the sodium channel blocking class of antiepileptic drugs, but it could have additional actions inasmuch as it has a broader spectrum of action than other sodium channel antiepileptic drugs such as phenytoin and carbamazepine and is effective in the treatment of the depressed phase of bipolar disorder, whereas other sodium channel blocking antiepileptic drugs are not.

In addition, lamotrigine shares few side-effects with other, unrelated anticonvulsants known to inhibit sodium channels), which further emphasizes its unique properties. Lamotrigine is inactivated by hepatic glucuronidation.

Availble Form:
Lamotrigine IR Pellets
Lamotrigine Granules

Umang Pharmatech equipments used for production of Lamotrigine Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Lamotrigine Pellets
Systematic (IUPAC) Name
Lamotrigine Pellets
Lamotrigine Pellets
Chemical data
CAS number : 84057-84-1
ATC code : N03AX09
PubChem : CID 3878
DrugBank : APRD00570
ChemSpider : 3741
UNII : U3H27498KS
KEGG : D00354
Formula : C9H7Cl2N5
Mol. mass : 256.091 g/mol

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