Letrozole Pellets

(Product under development)
Letrozole PelletsLetrozole (INN, trade name Femara) is an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery.

Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Estrogens then bind to an estrogen receptor, which causes cells to divide.

Letrozole prevents the aromatase from producing estrogens by competitive, reversible binding to the heme of its cytochrome P450 unit.

The action is specific, and letrozole does not reduce production of mineralo- or corticosteroids.

Availble Form:
Letrozole Pellets
Letrozole Granules

Umang Pharmatech equipments used for production of Letrozole Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.


Letrozole Pellets
Systematic (IUPAC) Name
Letrozole Pellets
Identifiers
Letrozole Pellets
Chemical data
4,4'-(1,2,4-triazol-1-ylmethyl)dibenzonitrile
CAS number : 112809-51-5
ATC code : L02BG04
PubChem : CID 3902
DrugBank : APRD01066
ChemSpider : 3765
UNII : 7LKK855W8I
KEGG : D00964
ChEBI : CHEBI:6413
ChEMBL : CHEMBL1444
Formula : C17H11N5
Mol. mass : 285.303 g/mol


* All transactions are carried out in conformity with patent laws applicable in the user country. Active pharmaceutical ingredients or formulations thereof will not be supplied in countries where the same is under patent protection except as and if permitted under law of the country for research and development purposes only.
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