Melatonin Pellets

(Product under development)
Melatonin PelletsMelatonin also known chemically as N-acetyl-5-methoxytryptamine, is a naturally occurring compound found in animals, plants and microbes. In animals, circulating levels of the hormone melatonin vary in a daily cycle, thereby allowing the entrainment of the circadian rhythms of several biological functions.

Many biological effects of melatonin are produced through activation of melatonin receptors, while others are due to its role as a pervasive and powerful antioxidant, with a particular role in the protection of nuclear and mitochondrial DNA.

In mammals, melatonin is secreted into the blood by the pineal gland in the brain. Known as the "hormone of darkness" it is secreted in darkness in both day-active (diurnal) and night-active (nocturnal) animals.

It may also be produced by a variety of peripheral cells such as bone marrow cells, lymphocytes and epithelial cells. Usually, the melatonin concentration in these cells is much higher than that found in the blood but it does not seem to be regulated by the photoperiod.

Melatonin-rich plant feed, such as rice, ingested by chicks has been shown to reach and bind to melatonin receptors in their brains. No food has been found to elevate plasma melatonin levels in humans.

Products containing melatonin have been available over-the-counter as a dietary supplement in the United States since the mid-1990s. In many other countries, the over-the-counter sale of this neurohormone is not permitted or requires a prescription, and the U.S. Postal Service lists unapproved melatonin preparations among items prohibited by Germany.

Available Form:
Melatonin Pellets
Melatonin Granules

Umang Pharmatech equipments used for production of Melatonin Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Melatonin Pellets
Systematic (IUPAC) Name
Melatonin Pellets
Identifiers
Melatonin Pellets
Chemical data
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ethanamide
CAS number : 73-31-4
ATC code : N05CH01
PubChem : CID 896
IUPHAR ligand : 224
DrugBank : DB01065
ChemSpider : 872
UNII : JL5DK93RCL
KEGG : D08170
ChEBI : CHEBI:16796
ChEMBL : CHEMBL45
Formula : C13H16N2O2
Mol. mass : 232.278 g/mol


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