Metformin Pellets

Metformin PelletsMetformin is an oral antidiabetic drug in the biguanide class.

It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function. Evidence is also mounting for its efficacy in gestational diabetes, although safety concerns still preclude its widespread use in this setting.

It is also used in the treatment of polycystic ovary syndrome, and has been investigated for other diseases where insulin resistance may be an important factor.

When prescribed appropriately, metformin causes few adverse effects—the most common is gastrointestinal upset—and is associated with a low risk of hypoglycemia. Lactic acidosis (a buildup of lactate in the blood) can be a serious concern in overdose and when it is prescribed to people with contraindications, but otherwise, there is no significant risk.

Metformin helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and is the only antidiabetic drug that has been conclusively shown to prevent the cardiovascular complications of diabetes. As of 2010, metformin is one of only two oral antidiabetics in the World Health Organization Model List of Essential Medicines.

Available Form:
Metformin SR Pellets
Metformin Granules

Umang Pharmatech equipments used for production of Metformin Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Metformin Pellets
Systematic (IUPAC) Name
Metformin Pellets
Identifiers
Metformin Pellets
Chemical data
N,N-dimethylimidodicarbonimidic diamide
CAS number : 657-24-9
ATC code : A10BA02
A10BD02 (with sulfonylureas) A10BD03 (with rosiglitazone) A10BD05 (with pioglitazone) A10BD07 (with sitagliptin)
A10BD08 (with vildagliptin)
PubChem : CID 4091
DrugBank : APRD01099
ChemSpider : 3949
UNII : 9100L32L2N
KEGG : D04966
ChEMBL : CHEMBL1431
Formula : C4H11N5
Mol. mass : 129.164 g/mol (free)
165.63 g/mol (HCl)


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