Minocycline Pellets

(Product under development)
Minocycline PelletsMinocycline is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group. It is a bacteriostatic antibiotic, classified as a long-acting type.

As a result of its long half-life it generally has serum levels 2-4 times that of the simple water-soluble tetracyclines (150 mg giving 16 times the activity levels compared to 250 mg oftetracycline at 24–48 hours).

Minocycline is the most lipid-soluble of the tetracycline-class antibiotics, giving it the greatest penetration into the prostate and brain, but also the greatest amount of central nervous system (CNS)-related side effects.

For this reason also, minocycline is a relatively poor tetracycline-class antibiotic for urinary pathogens sensitive to this antibiotic class, as its solubility in water, and levels in the urine, are less than all other tetracyclines.

Minocycline was originally discovered by Lederle Laboratories and marketed under the brand name Minocin.

Available Form:
Minocycline Pellets
Minocycline Granules

Umang Pharmatech equipments used for production of Minocycline Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Minocycline Pellets
Systematic (IUPAC) Name
Minocycline Pellets
Identifiers
Minocycline Pellets
Chemical data
(2E,4S,4aR,5aS,12aR)- 2-(amino-hydroxy-methylidene)- 4,7-bis(dimethylamino)- 10,11,12a-trihydroxy-4a,5,5a,6- tetrahydro-4H-tetracene- 1,3,12-trione[1]
OR
(4S,4aS,5aR,12aS,Z)-2-[amino(hydroxy)methylene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydrotetracene-1,3,12(2H,4H,12aH)-trione
CAS number : 10118-90-8
ATC code : J01AA08 A01AB23
PubChem : CID 24960
DrugBank : APRD00547
ChemSpider : 16735907
UNII : FYY3R43WGO
KEGG : D05045
ChEMBL : CHEMBL1434
Formula : C23H27N3O7
Mol. mass : 457.477


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