Montelukast Pellets

(Product under development)
Montelukast PelletsMontelukast (trade names Singulair and Montelo-10) is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.

It is usually administered orally. Montelukast is a CysLT1 antagonist; that it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it

This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.

Because of its method of operation, it is not useful for the treatment of acute asthma attacks. Again because of its very specific focus of operation, it does not interact with other asthma medications such as theophylline.

Another leukotriene receptor antagonist is zafirlukast (Accolate), taken twice daily. Zileuton (Zyflo), an asthma drug taken four times per day, blocks leukotriene synthesis by inhibiting 5-lipoxygenase, an enzyme of the eicosanoid synthesis pathway.

The Mont in Montelukast stands for Montreal, the place where Merck developed the drug.

Available Form:
Montelukast Pellets
Montelukast Granules

Umang Pharmatech equipments used for production of Montelukast Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.


Montelukast Pellets
Systematic (IUPAC) Name
Montelukast Pellets
Identifiers
Montelukast Pellets
Chemical data
(S,E)-2-(1-((1-(3-(2-(7-chloroquinolin
-2-yl)vinyl)phenyl)-3-(2-(2
-hydroxypropan-2-yl)phenyl)propylthio)
methyl)cyclopropyl)acetic acid
CAS number : 158966-92-8
ATC code : R03DC03
PubChemr : CID 5281040
DrugBank : APRD00434
ChemSpider : 4444507
UNII : MHM278SD3E
KEGG : D08229
ChEBI : CHEBI:50730
ChEMBL : CHEMBL787
Formula : C35H36ClNO3S
Mol. mass : 586.184 g/mol


* All transactions are carried out in conformity with patent laws applicable in the user country. Active pharmaceutical ingredients or formulations thereof will not be supplied in countries where the same is under patent protection except as and if permitted under law of the country for research and development purposes only.
Extruder Spheronizer Email Us Umang Pharmatech
TESTIMONIAL