Quinine Pellets

(Product under development)
Quinine PelletsQuinine is a natural white crystalline alkaloid havingantipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste.

It is a stereoisomer of quinidine which, unlike quinine, is an anti-arrhythmic. Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclicquinuclidine.

Though it has been synthesized in the lab, the bark of the cinchona tree is the only known natural source of quinine.

The medicinal properties of the cinchona tree were originally discovered by the Quechua Indians of Peru and Bolivia; later, the Jesuits were the first to bring the cinchona to Europe.

Quinine was the first effective treatment for malaria caused by Plasmodium falciparum, appearing in therapeutics in the 17th century. It remained the antimalarial drug of choice until the 1940s, when other drugs replaced it.

Since then, many effective antimalarials have been introduced, although quinine is still used to treat the disease in certain critical situations, i.e. as in impoverished regions.

Quinine is available with a prescription in the United States and over-the-counter, in very small quantities, in tonic water. Quinine is also used to treat lupus andarthritis. Until recently, quinine was also a common "off-label" treatment for nocturnal leg cramps. This practice is now considered dubious by the FDA.

Quinine is very sensitive to ultraviolet light (UV) and will fluoresce in direct sunlight, due to its highly conjugated resonance structure (see Quinoline).

Available Form:
Quinine Pellets
Quinine Granules

Umang Pharmatech equipments used for production of Quinine Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Quinine Pellets
Systematic (IUPAC) Name
Quinine Pellets
Identifiers
Quinine Pellets
Chemical data
(R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)- 8-vinylquinuclidin-2-yl)methanol
CAS number : 130-95-0
ATC code : M09AA01 P01BC01
PubChem : CID 8549
DrugBank : DB00468
ChemSpider : 84989
UNII : A7V27PHC7A
KEGG : D08460
ChEMBL : CHEMBL170
Formula : C20H24N2O2
Mol. mass : 324.417 g/mol


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