Raloxifene Pellets

(Product under development)
Raloxifene PelletsRaloxifene is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women.

In 2006, the National Cancer Institute announced that raloxifene was as effective as tamoxifen in reducing the incidence of breast cancer in postmenopausal women at increased risk. A major adverse effect of tamoxifen is uterine cancer; raloxifene had fewer uterine cancers.

Tamoxifen increased the risk of cataracts, but raloxifene did not. Both groups had more blood clots in veins and the lungs, but that side effect was more common with tamoxifen than raloxifene.

On September 14, 2007, the U.S. Food and Drug Administration announced approval of raloxifene for reducing the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer. An editorial in Lancet Oncology criticized the way that information about the drug was released.[6

Available Form:
Raloxifene Pellets
Raloxifene Granules

Umang Pharmatech equipments used for production of Raloxifene Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Raloxifene Pellets
Systematic (IUPAC) Name
Raloxifene Pellets
Raloxifene Pellets
Chemical data
[6-hydroxy-2-(4-hydroxyphenyl)- benzothiophen-3-yl]- [4-[2-(1-piperidyl)ethoxy]phenyl] -methanone
CAS number : 84449-90-1
ATC code : G03XC01
PubChem : CID 5035
DrugBank : APRD00400
ChemSpider : 4859
ChEBI : CHEBI:8772
Formula : C28H27NO4S
Mol. mass : 473.584 g/mol

* All transactions are carried out in conformity with patent laws applicable in the user country. Active pharmaceutical ingredients or formulations thereof will not be supplied in countries where the same is under patent protection except as and if permitted under law of the country for research and development purposes only.
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