Tadalafil Pellets

Tadalafil PelletsTadalafil is a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction(ED) under the name Cialis; and under the name Adcirca for the treatment of pulmonary arterial hypertension.

It initially was developed by the biotechnology company ICOS, and then again developed and marketed world-wide. Cialis tablets, in 5 mg, 10 mg, and 20 mg doses, are yellow, film-coated, and almond-shaped. The approved dose for pulmonary arterial hypertension is 40 mg (two 20-mg tablets) once daily.

On November 21, 2003 the Food and Drug Administration approved tadalafil (as Cialis) for sale in the United States as the third ED prescription drug pill (after sildenafil citrate (Viagra) andvardenafil (Levitra)).

Cialis's 36-hour effectiveness earned it the nickname, "The Weekend Pill"; like sildenafil and vardenafil, tadalafil is recommended as an 'as needed' medication. Cialis is the only one of the three that is also offered as a once-daily medication.

Moreover, tadalafil was approved in May 2009 in the United States for the treatment of pulmonary arterial hypertension and is currently under regulatory review in other regions for this condition.

Available Form:
Tadalafil Pellets
Tadalafil Granules

Umang Pharmatech equipments used for production of Tadalafil Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Tadalafil Pellets
Systematic (IUPAC) Name
Tadalafil Pellets
Tadalafil Pellets
Chemical data
(6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1', 2':1,6] pyrido[3,4-b]indole-1,4-dione
CAS number : 171596-29-5
ATC code : G04BE08
PubChem : CID 110635
DrugBank : APRD00071
ChemSpider : 99301
Formula : C22H19N3O4
Mol. mass : 389.404 g/mol

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